Micronit federates in a national research network academic research teams (CNRS, INSERM and CEA) interested  by the tumor microenvironment. The consortium includes 27 teams (17 in the GDR Micronit 2015/2018 and 10 associated teams) and covers the main hematological malignancies (myelodysplasia, acute leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, lymphomas, myelomas) and the majority of solid tumors (sarcomas, glioblastomas, hepatocellular carcinoma, breast cancers, prostate cancers , kidney cancer, ovarian cancer, melanoma).

 

Micronit groups medical skills as well as specific scientific and technological expertise (adhesion, angiogenesis, biomechanics, stem cells, stromal cells, domiciliation, hypoxia, imaging, inflammation, extracellular matrix, metabolism, 2D and 3D modeling, signaling) to optimize the French research on the following three axes:

 

• Axis #1 : "Structure of the niche : composition and cellular/molecular organisation"

• Axis #2 : "Dynamics of the interaction niche-tumor cells"

• Axis #3 : "Biomarkers and therapeutic targeting of tumor niches"

 

​