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2020

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- Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency. Hualong Bai1*, Nirvana Sadaghianloo*, Jolanta Gorecka, Shirley Liu, Shun Ono, Abhay B. Ramachandra, Sophie Bonnet, Nathalie M. Mazure, Serge Declemy,
Jay D. Humphrey, Alan Dardik. Sci. Transl. Med. 12, eaax7613 (2020)

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- Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites.

Bosc C, Broin N, Fanjul M, Saland E, Farge T, Courdy C, Batut A, Masoud R, Larrue C, Skuli S, Espagnolle N, Pagès JC, Carrier A, Bost F, Bertrand-Michel J, Tamburini J, Récher C, Bertoli S, Mansat-De Mas V, Manenti S, Sarry JE, Joffre C. Nat Commun. 2020 Aug 13;11(1):4056.

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- Cyclin D1 targets hexokinase 2 to control aerobic glycolysis in myeloma cells. Caillot M, Bourgeais J, Dakik H, Costé É, Mazure NM, Lelièvre É, Coqueret O, Hérault O, Mazurier F, Sola B. Oncogenesis. 2020 Jul 24;9(7):68.

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- Resveratrol and HIV-protease inhibitors control UCP1 expression through opposite effects on p38 MAPK phosphorylation in human adipocytes. Ravaud C, Paré M, Yao X, Azoulay S, Mazure NM, Dani C, Ladoux A. J Cell Physiol. 2020 Feb;235(2):1184-1196. 

 

- Co-culture of human fibroblasts, smooth muscle and endothelial cells promotes osteopontin induction in hypoxia. Sadaghianloo N, Contenti J, Dufies M, Parola J, Rouleau M, Lee S, Peyron JF, Fabbri L, Hassen-Khodja R, Pouysségur J, Bost F, Jean-Baptiste E, Dardik A, Mazure NM. J Cell Mol Med. 2020 Mar;24(5):2931-2941. 

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- Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients.

Fabbri L, Dufies M, Lacas-Gervais S, Gardie B, Gad-Lapiteau S, Parola J, Nottet N, Meyenberg Cunha de Padua M, Contenti J, Borchiellini D, Ferrero JM, Leclercq NR, Ambrosetti D, Mograbi B, Richard S, Viotti J, Chamorey E, Sadaghianloo N, Rouleau M, Craigen WJ, Mari B, Clavel S, Pagès G, Pouysségur J, Bost F, Mazure NM. Theranostics. 2020 Feb 3;10(6):2696-2713.

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- microRNA-375 regulates glucose metabolism-related signaling for insulin secretion. Dumortier O, Fabris G, Pisani DF, Casamento V, Gautier N, Hinault C, Lebrun P, Duranton C, Tauc M, Dalle S, Kerr-Conte J, Pattou F, Prentki M, Van Obberghen E. J Endocrinol. 2020 Jan 1;244(1):189-200. 

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2019

- Role of Hypoxia and Metabolism in the Development of Neointimal Hyperplasia in Arteriovenous Fistulas. Sadaghianloo N, Contenti J, Dardik A, Mazure NM. Int J Mol Sci. 2019 Oct 29;20(21). Review.

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- PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness. Kaminski L, Torrino S, Dufies M, Djabari Z, Haider R, Roustan FR, Jaune E, Laurent K, Nottet N, Michiels JF, Gesson M, Rocchi S, Mazure NM, Durand M, Tanti JF, Ambrosetti D, Clavel S, Ben-Sahra I, Bost F. Cancer Res. 2019 Jul 1;79(13):3268-3280.

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- UBTD1 is a mechano-regulator controlling cancer aggressiveness. Torrino S, Roustan FR, Kaminski L, Bertero T, Pisano S, Ambrosetti D, Dufies M, Uhler JP, Lemichez E, Mettouchi A, Gesson M, Laurent K, Gaggioli C, Michiels JF, Lamaze C, Bost F, Clavel S. EMBO Rep. 2019 Apr;20(4).

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- Hypoxia protects against the cell death triggered by oxovanadium-galactomannan complexes in HepG2 cells. Meyenberg Cunha-de Padua M, Noleto GR, de Oliveira Petkowicz CL, Cadena SMSC, Bost F, Pouysségur J, Mazure NM. Cell Mol Biol Lett. 2019 Mar 22;24:18.

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- Resveratrol and HIV-protease inhibitors control UCP1 expression through opposite effects on p38 MAPK phosphorylation in human adipocytes. Ravaud C, Paré M, Yao X, Azoulay S, Mazure NM, Dani C, Ladoux A. J Cell Physiol. 2020 Feb;235(2):1184-1196.

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- The metabolic modulator PGC-1α in cancer.Bost F, Kaminski L. Am J Cancer Res. 2019 Feb 1;9(2):198-211. Review.

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- Primary Cilium in Cancer Hallmarks. Fabbri L, Bost F, Mazure NM. Int J Mol Sci. 2019 Mar 16;20(6). Review.

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- Is Testicular Germ Cell Cancer Estrogen Dependent? The Role of Endocrine Disrupting Chemicals. Fénichel P, Chevalier N. Endocrinology. 2019 Dec 1;160(12):2981-2989. Review. 

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- Endocrine Disrupting Chemicals Interfere With Leydig Cell Hormone Pathways During Testicular Descent in Idiopathic Cryptorchidism. Fénichel P, Chevalier N, Lahlou N, Coquillard P, Wagner-Mahler K, Pugeat M, Panaïa-Ferrari P, Brucker-Davis F.  Front Endocrinol (Lausanne). 2019 Jan 10;9:786. Review. 

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- Argonaute-2 is associated to brown adipose tissue activation. Roger E, Dumortier O, Pisani DF, Gautier N, Van Obberghen E, Hinault C. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2393-2402. 

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2018

-Protein N-glycosylation alteration and glycolysis inhibition both contribute to the antiproliferative action of 2-deoxyglucose in breast cancer cells. Berthe A, Zaffino M, Muller C, Foulquier F, Houdou M, Schulz C, Bost F, De Fay E, Mazerbourg S, Flament S. Breast Cancer Res Treat. 2018 Jul 3. [Epub ahead of print]

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- Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation. Ferecatu I, Canal F, Fabbri L, Mazure NM, Bouton C, Golinelli-Cohen MP. PLoS One. 2018 Mar 29;13(3):e0194782.

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- Hypoxic-induced truncation of voltage-dependent anion channel 1 is mediated by both asparagine endopeptidase and calpain 1 activities. Pahima H, Reina S, Tadmor N, Dadon-Klein D, Shteinfer-Kuzmine A, Mazure NM, De Pinto V, Shoshan-Barmatz V. Oncotarget. 2018 Jan 31;9(16):12825-12841.

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- The two glycolytic markers GLUT1 and MCT1 correlate with tumor grade and survival in clear-cell renal cell carcinoma. Ambrosetti D, Dufies M, Dadone B, Durand M, Borchiellini D, Amiel J, Pouyssegur J, Rioux-Leclercq N, Pages G, Burel-Vandenbos F, Mazure NM. PLoS One. 2018 Feb 26;13(2):e0193477.

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- Immunosuppressive Mesenchymal Stromal Cells Derived from Human-Induced Pluripotent Stem Cells Induce Human Regulatory T Cells In Vitro and In Vivo. Roux C, Saviane G, Pini J, Belaïd N, Dhib G, Voha C, Ibáñez L, Boutin A, Mazure NM, Wakkach A, Blin-Wakkach C, Rouleau M. Front Immunol. 2018 Jan 25;8:1991.

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2017

- Sirtuin 7: a new marker of aggressiveness in prostate cancer. Haider R, Massa F, Kaminski L, Clavel S, Djabari Z, Robert G, Laurent K, Michiels JF, Durand M, Ricci JE, Tanti JF, Bost F, Ambrosetti D. Oncotarget. 2017 Aug 24;8(44):77309-77316.

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- The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells. Loubiere C, Clavel S, Gilleron J, Harisseh R, Fauconnier J, Ben-Sahra I, Kaminski L, Laurent K, Herkenne S, Lacas-Gervais S, Ambrosetti D, Alcor D, Rocchi S, Cormont M, Michiels JF, Mari B, Mazure NM, Scorrano L, Lacampagne A, Gharib A, Tanti JF, Bost F. Sci Rep. 2017 Jul 11;7(1):5040.

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- Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation. Andrio E, Lotte R, Hamaoui D, Cherfils J, Doye A, Daugaard M, Sorensen PH, Bost F, Ruimy R, Mettouchi A, Lemichez E. Sci Rep. 2017 Mar 20;7:44779.

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- Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells. Wang YY, Attané C, Milhas D, Dirat B, Dauvillier S, Guerard A, Gilhodes J, Lazar I, Alet N, Laurent V, Le Gonidec S, Biard D, Hervé C, Bost F, Ren GS, Bono F, Escourrou G, Prentki M, Nieto L, Valet P, Muller C. JCI Insight. 2017 Feb 23;2(4):e87489.

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- Age-Dependent Control of Energy Homeostasis by Brown Adipose Tissue in Progeny Subjected to Maternal Diet-Induced Fetal Programming. Dumortier O, Roger E, Pisani DF, Casamento V, Gautier N, Lebrun P, Johnston H, Lopez P, Amri EZ, Jousse C, Fafournoux P, Prentki M, Hinault C, Van Obberghen E. Diabetes. 2017 Mar;66(3):627-639.

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- Disrupting glucose-6-phosphate isomerase fully suppresses the "Warburg effect" and activates OXPHOS with minimal impact on tumor growth except in hypoxia. de Padua MC, Delodi G, Vučetić M, Durivault J, Vial V, Bayer P, Noleto GR, Mazure NM, Ždralević M, Pouysségur J. Oncotarget. 2017 Sep 18;8(50):87623-87637.

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- The Leukemic Stem Cell Niche: Adaptation to "Hypoxia" versus Oncogene Addiction. Cheloni G, Poteti M,Bono S, Masala E, Mazure NM, Rovida E, Lulli M, Dello Sbarba P. Stem Cells Int. 2017;2017:4979474.

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- The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells. Loubiere C, Clavel S, Gilleron J, Harisseh R, Fauconnier J, Ben-Sahra I, Kaminski L, Laurent K, Herkenne S, Lacas-Gervais S, Ambrosetti D, Alcor D, Rocchi S, Cormont M, Michiels JF, Mari B, Mazure NM, Scorrano L, Lacampagne A, Gharib A, Tanti JF, Bost F. Sci Rep. 2017 Jul 11;7(1):5040.

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- VDAC in cancer. Mazure NM. Biochim Biophys Acta. 2017 Aug;1858(8):665-673. Review.

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- New diabetogens? Fénichel P, Chevalier N. Environmental endocrine disruptors:  C R Biol. 2017 Sep-Oct;340(9-10):446-452. 

 

- Which origin for polycystic ovaries syndrome: Genetic, environmental or both? Fenichel P, Rougier C, Hieronimus S, Chevalier N. Ann Endocrinol (Paris). 2017 Jul;78(3):176-185. Review.

 

- Age-Dependent Control of Energy Homeostasis by Brown Adipose Tissue in Progeny Subjected to Maternal Diet-Induced Fetal Programming. Dumortier O, Roger E, Pisani DF, Casamento V, Gautier N, Lebrun P, Johnston H, Lopez P, Amri EZ, Jousse C, Fafournoux P, Prentki M, Hinault C, Van Obberghen E. Diabetes. 2017 Mar;66(3):627-639.  

 

2016

- Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimetics. Rubio-Patiño C, Bossowski JP, Villa E, Mondragón L, Zunino B, Proïcs E, Chiche J, Bost F, Verhoeyen E, Ricci JE. Oncotarget. 2016 Nov 8;7(45):73270-73279.

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- Energy disruptors: rising stars in anticancer therapy? Bost F, Decoux-Poullot AG, Tanti JF, Clavel S. Oncogenesis. 2016 Jan 18;5:e188. Review.

- Endocrine disruptors: A missing link in the pandemy of type 2 diabetes and obesity?.Chevalier N, Fénichel P. Presse Med. 2016 Jan;45(1):88-97. French.

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- News about VDAC1 in Hypoxia. Mazure NM. Front Oncol. 2016 Aug 30;6:193.

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- The K+ channel TASK1 modulates β-adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway. Pisani DF, Beranger GE, Corinus A, Giroud M, Ghandour RA, Altirriba J, Chambard JC, Mazure NM, Bendahhou S, Duranton C, Michiels JF, Frontini A, Rohner-Jeanrenaud F, Cinti S, Christian M, Barhanin J, Amri EZ. FASEB J. 2016 Feb;30(2):909-22.

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- Comment on "Effects of Atrazine on Estrogen Receptor α- and G Protein-Coupled Receptor 30-Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts". Chevalier N, Paul-Bellon R, Fénichel P. Environ Health Perspect. 2016 Apr;124(4):A64-5.